Sublingual Grass Immunotherapy (Grastek and Oralair)

There are currently 2 treatment options for sublingual grass immunotherapy

1. GRASTEK® (Standardized Allergen Extract, Timothy Grass (Phleum pratense) Sublingual Tablet) is an allergy immunotherapy tablet for the treatment of signs and symptoms of grass allergy. It is formulated as an orally disintegrating tablet designed to rapidly dissolve under the tongue. The active substance is a natural grass pollen extract which is purified and standardized from Timothy Grass. Each sublingual tablet has a strength of 2800 BAU.
INDICATIONS AND CLINICAL USE GRASTEK®  is indicated for reducing the signs and symptoms of moderate to severe seasonal Timothy and related grass pollen induced allergic rhinitis (with or without conjunctivitis) in adults and children 5 years of age and older confirmed by clinically relevant symptoms for at least two pollen seasons and a positive skin prick test who have responded inadequately, or are intolerant to conventional pharmacotherapy.Treatment with GRASTEK® should only be prescribed and initiated by physicians with adequate training and experience in the treatment of respiratory allergic diseases.Pediatrics (less than 5 years of age): Safety and efficacy in pediatric patients below 5 years of age have not been established.




2. ORALAIR® (Sweet Vernal, Orchard, Perennial Rye, Timothy, and Kentucky Blue Grass Mixed Pollens Allergen Extract) is a prescription medicine used for sublingual (under the tongue) immunotherapy prescribed to treat sneezing, runny or itchy nose, nasal congestion and itchy watery eyes due to grass pollen allergy. 

This formulation contains a mixture of all 5 types of grass pollen proteins

ORALAIR may be prescribed for people 10 to 65 years old.